enrique.sentandreu@iata.csic.es

Publications

• [1] J.L. Navarro, D. Alegre, M.A. Sentandreu, D. Rodrigo, E. Sentandreu, Proteome changes of tiger nut “horchata” drink induced by dynamic high pressure homogenization processing, Journal of Food Composition and Analysis. 117 (2023) 105132. https://doi.org/10.1016/j.jfca.2023.105132.
  [2] B. Garlito, M.A. Sentandreu, V. Yusà, M. Oliván, O. Pardo, E. Sentandreu, New insights into the search of meat quality biomarkers assisted by Orbitrap Tribrid untargeted metabolite analysis and chemometrics, Food Chemistry. 407 (2023) 135173. https://doi.org/10.1016/j.foodchem.2022.135173.
  [3] L.R. Beldarrain, E. Sentandreu, N. Aldai, M.Á. Sentandreu, I. Miller, Application of 2-D DIGE to study the effect of ageing on horse meat myofibrillar sub-proteome, Journal of Proteomics. 272 (2023) 104770. https://doi.org/10.1016/j.jprot.2022.104770.
  [4] E. Sentandreu, M.Á. Sentandreu, Chapter3 - Technological developments of food peptidomics, in: M.L. Pedrouso, D.F. Ruiz, J.M. Lorenzo (Eds.), Food Proteomics, Academic Press, 2022: pp. 49–76. https://doi.org/10.1016/B978-0-323-90889-4.00009-9.
  [5] C. Fuente-Garcia, E. Sentandreu, N. Aldai, M.A. Sentandreu, Optimization of a fluorogenic assay to determine caspase 3/7 activity in meat extracts, Food Sci. Technol. Int. 28 (2022) 128–134. https://doi.org/10.1177/1082013221993577.
  [6] C. Fuente-García, N. Aldai, E. Sentandreu, M. Oliván, D. Franco, S. García-Torres, M.Á. Sentandreu, Assessment of caspase activity in post mortem muscle as a way to explain characteristics of DFD beef, Journal of Food Composition and Analysis. 111 (2022) 104599. https://doi.org/10.1016/j.jfca.2022.104599.
  [7] L.R. Beldarrain, E. Sentandreu, N. Aldai, M.A. Sentandreu, Horse meat tenderization in relation to post-mortem evolution of the myofibrillar sub-proteome, Meat Science. 188 (2022) 108804. https://doi.org/10.1016/j.meatsci.2022.108804.
  [8] E. Sentandreu, C. Fuente-García, O. Pardo, M. Oliván, N. León, N. Aldai, V. Yusà, M.A. Sentandreu, Protein Biomarkers of Bovine Defective Meats at a Glance: Gel-Free Hybrid Quadrupole-Orbitrap Analysis for Rapid Screening, J. Agric. Food Chem. 69 (2021) 7478–7487. https://doi.org/10.1021/acs.jafc.1c02016.
  [9] E. Sentandreu, C. Fuente-García, J.L. Navarro, M.A. Sentandreu, A straightforward gel-free proteomics pipeline assisted by liquid isoelectric focusing (OFFGEL) and mass spectrometry analysis to study bovine meat proteome, Food Sci. Technol. Int. 27 (2021) 112–122. https://doi.org/10.1177/1082013220929144.
  [10] C. Fuente-García, M.A. Sentandreu, N. Aldai, M. Oliván, E. Sentandreu, Proteomic pipeline for biomarker hunting of defective bovine meat assisted by liquid chromatography-mass spectrometry analysis and chemometrics, Journal of Proteomics. 238 (2021) 104153. https://doi.org/10.1016/j.jprot.2021.104153.
  [11] C. Fuente-García, N. Aldai, E. Sentandreu, M. Oliván, D. Franco, S. García-Torres, L.J. R Barron, M.Á. Sentandreu, Caspase activity in post mortem muscle and its relation to cattle handling practices, Journal of the Science of Food and Agriculture. 101 (2021) 6258–6264. https://doi.org/10.1002/jsfa.11293.
  [12] C.M. Stinco, E. Sentandreu, P. Mapelli-Brahm, J.L. Navarro, I.M. Vicario, A.J. Meléndez-Martínez, Influence of high pressure homogenization and pasteurization on the in vitro bioaccessibility of carotenoids and flavonoids in orange juice, Food Chemistry. 331 (2020) 127259. https://doi.org/10.1016/j.foodchem.2020.127259.
  [13] E. Sentandreu, C.M. Stinco, I.M. Vicario, P. Mapelli-Brahm, J.L. Navarro, A.J. Meléndez-Martínez, High-pressure homogenization as compared to pasteurization as a sustainable approach to obtain mandarin juices with improved bioaccessibility of carotenoids and flavonoids, Journal of Cleaner Production. 262 (2020) 121325. https://doi.org/10.1016/j.jclepro.2020.121325.
  [14] C. Fuente‐Garcia, E. Sentandreu, N. Aldai, M. Oliván, M.Á. Sentandreu, Characterization of the Myofibrillar Proteome as a Way to Better Understand Differences in Bovine Meats Having Different Ultimate pH Values, PROTEOMICS. 20 (2020) 2000012. https://doi.org/10.1002/pmic.202000012.
  [15] M.D. Peris-Díaz, O. Rodak, S.R. Sweeney, A. Krężel, E. Sentandreu, Chemometrics-assisted optimization of liquid chromatography-quadrupole-time-of-flight mass spectrometry analysis for targeted metabolomics, Talanta. 199 (2019) 380–387. https://doi.org/10.1016/j.talanta.2019.02.075.
  [16] M.D. Peris-Díaz, S.R. Sweeney, O. Rodak, E. Sentandreu, S. Tiziani, R-MetaboList 2: A Flexible Tool for Metabolite Annotation from High-Resolution Data-Independent Acquisition Mass Spectrometry Analysis, Metabolites. 9 (2019) 187. https://doi.org/10.3390/metabo9090187.
  [17] C. Fuente-Garcia, N. Aldai, E. Sentandreu, M. Oliván, S. García-Torres, D. Franco, C. Zapata, M.A. Sentandreu, Search for proteomic biomarkers related to bovine pre-slaughter stress using liquid isoelectric focusing (OFFGEL) and mass spectrometry, Journal of Proteomics. 198 (2019) 59–65. https://doi.org/10.1016/j.jprot.2018.10.013.
  [18] M. Ballester, E. Sentandreu, G. Luongo, R. Santamaria, M. Bolonio, M.I. Alcoriza-Balaguer, M. Palomino-Schätzlein, A. Pineda-Lucena, J. Castell, A. Lahoz, R. Bort, Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells, Scientific Reports. 9 (2019) 1–12. https://doi.org/10.1038/s41598-019-54357-x.
  [19] T.A. Triplett, K.C. Garrison, N. Marshall, M. Donkor, J. Blazeck, C. Lamb, A. Qerqez, J.D. Dekker, Y. Tanno, W.-C. Lu, C.S. Karamitros, K. Ford, B. Tan, X.M. Zhang, K. McGovern, S. Coma, Y. Kumada, M.S. Yamany, E. Sentandreu, G. Fromm, S. Tiziani, T.H. Schreiber, M. Manfredi, L.I.R. Ehrlich, E. Stone, G. Georgiou, Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme, Nature Biotechnology. 36 (2018) 758–764. https://doi.org/10.1038/nbt.4180.
  [20] E. Sentandreu, M.D. Peris-Díaz, S.R. Sweeney, J. Chiou, N. Muñoz, S. Tiziani, A Survey of Orbitrap All Ion Fragmentation Analysis Assessed by an R MetaboList Package to Study Small-Molecule Metabolites, Chromatographia. 81 (2018) 981–994. https://doi.org/10.1007/s10337-018-3536-y.
  [21] M.D. Peris-Díaz, M.A. Sentandreu, E. Sentandreu, Multiobjective optimization of liquid chromatography–triple-quadrupole mass spectrometry analysis of underivatized human urinary amino acids through chemometrics, Analytical and Bioanalytical Chemistry. 410 (2018) 4275–4284. https://doi.org/10.1007/s00216-018-1083-x.
  [22] M.D. Peris-Díaz, B. Łydżba-Kopczyńska, E. Sentandreu, Raman spectroscopy coupled to chemometrics to discriminate provenance and geological age of amber, Journal of Raman Spectroscopy. 49 (2018) 842–851. https://doi.org/10.1002/jrs.5357.
  [23] S. Fadda, E. Sentandreu, M.A. Sentandreu, Peptidomics on Farm Animal Research, in: A.M. de Almeida, D. Eckersall, I. Miller (Eds.), Proteomics in Domestic Animals: From Farm to Systems Biology, Springer International Publishing, Cham, 2018: pp. 387–420. https://doi.org/10.1007/978-3-319-69682-9_19.
  [24] J.D. Bryant, S.R. Sweeney, E. Sentandreu, M. Shin, H. Ipas, B. Xhemalce, J. Momb, S. Tiziani, D.R. Appling, Deletion of the neural tube defect–associated gene Mthfd1l disrupts one-carbon and central energy metabolism in mouse embryos, J Biol Chem. 293 (2018) 5821–5833. https://doi.org/10.1074/jbc.RA118.002180.
  [25] L.R. Beldarrain, N. Aldai, B. Picard, E. Sentandreu, J.L. Navarro, M.A. Sentandreu, Use of liquid isoelectric focusing (OFFGEL) on the discovery of meat tenderness biomarkers, Journal of Proteomics. 183 (2018) 25–33. https://doi.org/10.1016/j.jprot.2018.05.005.
  [26] M.D. Peris-Díaz, M.I. Alcoriza-Balaguer, J.C. García-Cañaveras, F. Santonja, E. Sentandreu, A. Lahoz, RpeakChrom: Novel R package for the automated characterization and optimization of column efficiency in high-performance liquid chromatography analysis, ELECTROPHORESIS. 38 (2017) 2985–2995. https://doi.org/10.1002/elps.201700180.
  [27] X. Lu, A. Solmonson, A. Lodi, S.M. Nowinski, E. Sentandreu, C.L. Riley, E.M. Mills, S. Tiziani, The early metabolomic response of adipose tissue during acute cold exposure in mice, Scientific Reports. 7 (2017). https://doi.org/10.1038/s41598-017-03108-x.
  [28] A. Lodi, A. Saha, X. Lu, B. Wang, E. Sentandreu, M. Collins, M.G. Kolonin, J. DiGiovanni, S. Tiziani, Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism, Npj Precision Oncology. 1 (2017) 1–12. https://doi.org/10.1038/s41698-017-0024-z.
  [29] A. Chikhoune, M. Gagaoua, K.D. Nanema, A.S. Souleymane, K. Hafid, K. Aliane, S. Hadjal, K. Madani, E. Sentandreu, M.Á. Sentandreu, A. Boudjellal, M. Križman, I. Vovk, Antioxidant Activity of Hibiscus sabdariffa Extracts Incorporated in an Emulsion System Containing Whey Proteins: Oxidative Stability and Polyphenol–Whey Proteins Interactions, Arabian Journal for Science and Engineering. 42 (2017) 2247–2260. https://doi.org/10.1007/s13369-017-2428-z.
  [30] S. Tiziani, B. Wang, A. Saha, X. Lu, E. Sentandreu, A. Lodi, J. DiGiovanni, Combinatorial treatment with natural compounds leads to smaller prostate tumor size and key modulations of cell metabolism, The FASEB Journal. 30 (2016) lb141–lb141. https://doi.org/10.1096/fasebj.30.1_supplement.lb141.
  [31] S.R. Sweeney, E. Sentandreu, S. Tiziani, Abstract 3: Amino acid profiles indicate dependence on different metabolic pathways between leukemia subtypes, Cancer Res. 76 (2016) 3–3. https://doi.org/10.1158/1538-7445.AM2016-3.
  [32] X. Lu, B. Wang, A. Saha, E. Sentandreu, A. Lodi, J. DiGiovanni, S. Tiziani, Abstract 12: Combinatorial intervention with natural compounds induces key metabolic modulations for prostate cancer prevention and treatment, Cancer Res. 76 (2016) 12–12. https://doi.org/10.1158/1538-7445.AM2016-12.
  [33] M.J. Fabra, A. López-Rubio, E. Sentandreu, J.M. Lagaron, Development of multilayer corn starch-based food packaging structures containing β-carotene by means of the electro-hydrodynamic processing: Development of multilayer corn starch-based food…, Starch - Stärke. 68 (2016) 603–610. https://doi.org/10.1002/star.201500154.
  [34] E. Sentandreu, M. Cerdán-Calero, J.L. Navarro, Metabolite profiling of pigments from acid-hydrolysed persimmon (Diospyros kaki) extracts by HPLC-DAD/ESI-MSn analysis, Journal of Food Composition and Analysis. 38 (2015) 55–61. https://doi.org/10.1016/j.jfca.2014.10.010.
  [35] E. Sentandreu, M. Cerdán-Calero, J.M. Halket, J.L. Navarro, Rapid screening of low-molecular-weight phenols from persimmon ( Diospyros kaki ) pulp using liquid chromatography/UV-visible/electrospray mass spectrometry analysis, Journal of the Science of Food and Agriculture. 95 (2015) 1648–1654. https://doi.org/10.1002/jsfa.6867.
  [36] M. Cerdán-Calero, J.M. Sendra, E. Sentandreu, Determination of the antiradical activity and kinetics of pomegranate juice using 2,2-diphenylpicyrl-1-hydrazyl as the antiradical probe, Food Science and Technology International. 21 (2015) 277–283. https://doi.org/10.1177/1082013214533687.
  [37] A. Berto, A.B. Ribeiro, E. Sentandreu, N.E. de Souza, A.Z. Mercadante, R.C. Chisté, E. Fernandes, The seed of the Amazonian fruit Couepia bracteosa exhibits higher scavenging capacity against ROS and RNS than its shell and pulp extracts, Food & Function. 6 (2015) 3081–3090. https://doi.org/10.1039/c5fo00722d.
  [38] M. Tomás-Navarro, F. Vallejo, E. Sentandreu, J.L. Navarro, F.A. Tomás-Barberán, Volunteer Stratification Is More Relevant than Technological Treatment in Orange Juice Flavanone Bioavailability, Journal of Agricultural and Food Chemistry. 62 (2014) 24–27. https://doi.org/10.1021/jf4048989.
  [39] M.Á. Sentandreu, E. Sentandreu, Authenticity of meat products: Tools against fraud, Food Research International. 60 (2014) 19–29. https://doi.org/10.1016/j.foodres.2014.03.030.
  [40] J.L. Navarro, A. Tárrega, M.A. Sentandreu, E. Sentandreu, Partial purification and characterization of polyphenol oxidase from persimmon, Food Chemistry. 157 (2014) 283–289. https://doi.org/10.1016/j.foodchem.2014.02.063.
  [41] J.L. Navarro, L. Izquierdo, J.V. Carbonell, E. Sentandreu, Effect of pH, temperature and maturity on pectinmethylesterase inactivation of citrus juices treated by high-pressure homogenization, LWT - Food Science and Technology. 57 (2014) 785–788. https://doi.org/10.1016/j.lwt.2014.01.033.
  [42] M. Cerdán-Calero, L. Izquierdo, J.M. Halket, E. Sentandreu, Evaluation of minimal processing of orange juice by automated data analysis of volatiles and nonvolatile polar compounds determined by gas chromatography coupled to mass spectrometry, International Journal of Food Science & Technology. 49 (2014) 1432–1440. https://doi.org/10.1111/ijfs.12539.
  [43] E. Sentandreu, M. Cerdán-Calero, J.M. Sendra, Phenolic profile characterization of pomegranate (Punica granatum) juice by high-performance liquid chromatography with diode array detection coupled to an electrospray ion trap mass analyzer, Journal of Food Composition and Analysis. 30 (2013) 32–40. https://doi.org/10.1016/j.jfca.2013.01.003.
  [44] M. Cerdán-Calero, L. Izquierdo, E. Sentandreu, Valencia Late orange juice preserved by pulp reduction and high pressure homogenization: Sensory quality and gas chromatography–mass spectrometry analysis of volatiles, LWT - Food Science and Technology. 51 (2013) 476–483. https://doi.org/10.1016/j.lwt.2012.11.016.
  [45] J.V. Carbonell, J.L. Navarro, L. Izquierdo, E. Sentandreu, Influence of high pressure homogenization and pulp reduction on residual pectinmethylesterase activity, cloud stability and acceptability of Lane Late orange juice: A study to obtain high quality orange juice with extended shelf life, Journal of Food Engineering. 119 (2013) 696–700. https://doi.org/10.1016/j.jfoodeng.2013.06.041.
  [46] E. Sentandreu, J.L. Navarro, J.M. Sendra, Identification of New Coloured Anthocyanin–Flavanol Adducts in Pressure-Extracted Pomegranate (Punica granatum L.) Juice by High-Performance Liquid Chromatography/Electrospray Ionization Mass Spectrometry, Food Analytical Methods. 5 (2012) 702–709. https://doi.org/10.1007/s12161-011-9301-6.
  [47] M. Cerdán-Calero, J.M. Sendra, E. Sentandreu, Gas chromatography coupled to mass spectrometry analysis of volatiles, sugars, organic acids and aminoacids in Valencia Late orange juice and reliability of the Automated Mass Spectral Deconvolution and Identification System for their automatic identification and quantification, Journal of Chromatography A. 1241 (2012) 84–95. https://doi.org/10.1016/j.chroma.2012.04.014.
  [48] E. Betoret, E. Sentandreu, N. Betoret, P. Codoñer-Franch, V. Valls-Bellés, P. Fito, Technological development and functional properties of an apple snack rich in flavonoid from mandarin juice, Innovative Food Science & Emerging Technologies. 16 (2012) 298–304. https://doi.org/10.1016/j.ifset.2012.07.003.
  [49] E. Betoret, E. Sentandreu, N. Betoret, P. Fito, Homogenization pressures applied to citrus juice manufacturing. Functional properties and application, Journal of Food Engineering. 111 (2012) 28–33. https://doi.org/10.1016/j.jfoodeng.2012.01.035.
  [50] M.A. Sentandreu, E. Sentandreu, Peptide biomarkers as a way to determine meat authenticity, Meat Science. 89 (2011) 280–285. https://doi.org/10.1016/j.meatsci.2011.04.028.
  [51] E. Sentandreu, M. del C. Gurrea, N. Betoret, J.L. Navarro, Changes in orange juice characteristics due to homogenization and centrifugation, Journal of Food Engineering. 105 (2011) 241–245. https://doi.org/10.1016/j.jfoodeng.2011.02.027.
  [52] J.V. Carbonell, A. Tárrega, M.C. Gurrea, E. Sentandreu, Chilled orange juices stabilized by centrifugation and differential heat treatments applied to low pulp and pulpy fractions, Innovative Food Science & Emerging Technologies. 12 (2011) 315–319. https://doi.org/10.1016/j.ifset.2011.04.009.
  [53] E. Sentandreu, J.L. Navarro, J.M. Sendra, LC-DAD-ESI/MS n Determination of Direct Condensation Flavanol−Anthocyanin Adducts in Pressure Extracted Pomegranate ( Punica granatum L.) Juice, Journal of Agricultural and Food Chemistry. 58 (2010) 10560–10567. https://doi.org/10.1021/jf101978z.
  [54] P. Codoñer-Franch, A.B. López-Jaén, A. De La Mano-Hernández, E. Sentandreu, R. Simó-Jordá, V. Valls-Bellés, Oxidative markers in children with severe obesity following low-calorie diets supplemented with mandarin juice: Oxidative stress and diet, Acta Paediatrica. 99 (2010) 1841–1846. https://doi.org/10.1111/j.1651-2227.2010.01903.x.
  [55] E. Sentandreu, J.L. Navarro, J.M. Sendra, Reduction Kinetics of the Antiradical Probe 2,2-Diphenyl-1-picrylhydrazyl in Methanol and Acetonitrile by the Antiradical Activity of Protocatechuic Acid and Protocatechuic Acid Methyl Ester, Journal of Agricultural and Food Chemistry. 56 (2008) 4928–4936. https://doi.org/10.1021/jf800142q.
  [56] P. Codoñer-Franch, A.B. López-Jaén, P. Muñiz, E. Sentandreu, V.V. Bellés, Mandarin Juice Improves the Antioxidant Status of Hypercholesterolemic Children:, Journal of Pediatric Gastroenterology and Nutrition. 47 (2008) 349–355. https://doi.org/10.1097/MPG.0b013e31816a8cdb.
  [57] E. Sentandreu, J.L. Navarro, J.M. Sendra, Effect of technological processes and storage on flavonoids content and total, cumulative fast-kinetics and cumulative slow-kinetics antiradical activities of citrus juices, European Food Research and Technology. 225 (2007) 905–912. https://doi.org/10.1007/s00217-006-0500-0.
  [58] E. Sentandreu, L. Izquierdo, J.M. Sendra, Total, cumulative fast-kinetics and cumulative slow-kinetics antiradical activities of juices from clementine (Citrus clementina), clementine-hybrids and satsuma (Citrus unshiu) cultivars and their utility as discriminant variables, European Food Research and Technology. 225 (2007) 271–278. https://doi.org/10.1007/s00217-006-0414-x.
  [59] E. Sentandreu, L. Izquierdo, J.M. Sendra, Differentiation of juices from clementine (Citrus clementina), clementine-hybrids and satsuma (Citrus unshiu) cultivars by statistical multivariate discriminant analysis of their flavanone-7-O-glycosides and fully methoxylated flavones content as determined by liquid chromatography, European Food Research and Technology. 224 (2007) 421–429. https://doi.org/10.1007/s00217-006-0330-0.
  [60] J.M. Sendra, E. Sentandreu, J.L. Navarro, Kinetic Model for the Antiradical Activity of the Isolated p -Catechol Group in Flavanone Type Structures Using the Free Stable Radical 2,2-Diphenyl-1-picrylhydrazyl as the Antiradical Probe, Journal of Agricultural and Food Chemistry. 55 (2007) 5512–5522. https://doi.org/10.1021/jf070689s.
  [61] E. Sentandreu, L. Carbonell, D. Rodrigo, J.V. Carbonell, Pulsed Electric Fields Versus Thermal Treatment: Equivalent Processes To Obtain Equally Acceptable Citrus Juices, Journal of Food Protection. 69 (2006) 2016–2018. https://doi.org/10.4315/0362-028X-69.8.2016.
  [62] J.M. Sendra, E. Sentandreu, J.L. Navarro, Reduction kinetics of the free stable radical 2,2-diphenyl-1-picrylhydrazyl (DPPH•) for determination of the antiradical activity of citrus juices, European Food Research and Technology. 223 (2006) 615–624. https://doi.org/10.1007/s00217-005-0243-3.
  [63] E. Sentandreu, L. Carbonell, J.V. Carbonell, L. Izquierdo, Effects of Heat Treatment Conditions on Fresh Taste and on Pectinmethylesterase Activity of Chilled Mandarin and Orange Juices, Food Science and Technology International. 11 (2005) 217–222. https://doi.org/10.1177/1082013205054291.
  [64] J.M. Sendra, E. Sentandreu, J.V. Carbonell, Time Evolution of Exposed Hydrophobicity of Water-Soluble Proteins During their Depolymerisation by Endo-Proteases, Food Science and Technology International. 10 (2004) 399–408. https://doi.org/10.1177/1082013204049487.
  [65] E. Sentandreu, J.V. Carbonell, J.M. Sendra, Monitoring of chemical and enzymatic hydrolysis of water-soluble proteins using flow-injection analysis with fluorescence detection and an aqueous eluant containing 2-p-toluidinylnaphthalene-6-sulfonate as the fluorescent probe, Biotechnology and Bioengineering. 78 (2002) 829–833. https://doi.org/10.1002/bit.10265.