
Biography
Puesto actual: Cientifico Titular - Instituto de Agroquímica y Tecnología de Alimentos (CSIC), Valencia, España desde 2001.
Post-docs:
Instituto de Agroquímica y Tecnología de Alimentos (CSIC), Valencia, España (1997-2001).
Dipart. di Fisiol. delle Piante Colt. e Chimica Agraria, Universita degli Studi di Milano, Milano, Italia (1997).
Instituto de Agroquímica y Tecnología de Alimentos (CSIC), Valencia, España (1994-1996).
Molecular Genetics of Industrial Micro-organisms, Wageningen Agricultural University, Holanda (1991-1993).
Molecular Genetics Unit, University of St. Andrews, Escocia (1986-1990).
Inst. of Genetics, University of Glasgow, Escocia (1985).
Dept. of Medical Genetics, Queen's University, Belfast, Irlanda Norte/Dept of Genetics, Trinity College, Dublin, Ireland (1982-1984).
Dept. of Biochemistry, University of Glasgow, Escocia (1981).
Ph.D. thesis: A Study of Proteins associated with Active Genes. Beatson Institute, University of Glasgow, Escocia. (1982).
Projects
Publications
The Loss-of-Function Mutation aldA67 leads to enhanced α-L-Rhamnosidase production by Aspergillus nidulans. 2022. M. Orejas, A.P. MacCabe. Journal of Fungi 8, 1181. (DOI: https://doi.org/10.3390/jof8111181).
Agrobacterium tumefaciens-mediated transformation of NHEJ mutant Aspergillus nidulans conidia: an efficient tool for targeted gene recombination using selectable nutritional markers. 2021. V. Casado-del Castillo, A.P. MacCabe, M. Orejas. Journal of Fungi 7, 961-975. (DOI: https://doi.org/10.3390/jof7110961).
Identification of the genes encoding the catalytic steps corresponding to LRA4 (L-KDR aldolase) and LADH (L-lactaldehyde dehydrogenase) in Aspergillus nidulans: evidence for involvement of the loci AN9425/lraD and AN0544/aldA in the L-rhamnose catabolic pathway. 2021. A. MacCabe, G. Sanmartin, M. Orejas. Environmental Microbiology 23, 2420-2432. (DOI: http://dx.doi.org/10.1111/1462-2920.15439).
Catabolism of L-rhamnose in A. nidulans proceeds via the non-phosphorylated pathway and is glucose repressed by a CreA-independent mechanism. 2020. A. P. MacCabe, E. I. Ninou, E. Pardo, M. Orejas. Microbial Cell Factories 19, article 188 (15 páginas). (DOI: https://doi.org/10.1186/s12934-020-01443-9).
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus. 2017. R.P. de Vries et al. Genome Biology 18, 28-73. (DOI: https://doi.org/10.1186/s13059-017-1151-0).
Patents
- Request number:201030913Title:Endoxilanasa termorresistente obtenida por mutagénesis y su aplicación al proceso de obtención de bioetanolDate of the request:Monday, 14 June, 2010